萊姆病的病原體柏氏疏螺旋體擁有特殊的能力，能夠用錳，而不是鐵製造酶，並且幫助它躲避免疫系統的防禦和偵測其存在。
(The Lyme disease pathogen Borrelia burgdorferi has an unusual ability to substitute manganese for iron to build enzymes, which helps it elude immune defenses as well as tests to detect it.)